He personifies the archetype of the mad scientist, viewing everyone as objects to be dissected in the lab. He takes great pride in his experiments and the things he has created and condemns the concept of perfection. He has made extensive modifications to his body: his left arm can extend like a grappling hook, he can form a scythe by pulling out his ears, and can even replace his organs with dummies. Mayuri has little regard for life or allegiances, even going as far as turning his own subordinates into human bombs on one occasion.